La Academia de Ciencias de Cuba (ACC) entregará hoy en La Habana la condición de miembro Correspondiente al doctor en Ciencias Mark Rasenick, distinguido profesor de Fisiología, Biofísica y Psiquiatría de la Universidad de Illinois, Chicago, Estados Unidos. Read the full December 2018 article via Google Translate or in the original Spanish at cubasi.cu.Details
Pax’s biomarker technology suggests a different site of action for the “rapid acting antidepressant” ketamine.
Ketamine acts within hours to ameliorate depression for some. This common drug of abuse is generally thought to work by blocking a receptor for the excitatory neurotransmitter, glutamate. A recent study by Rasenick and colleagues, using Pax Biomarker technology, was published in the Nature journal, “Molecular Psychiatry” . The paper reveals that one mechanism of ketamine action is independent of the NMDA receptor. Curiously, ketamine elicits the same actions as any other antidepressant observed with MoodMarkSCREEN, but rather than 3 days of incubation, the “rabid acting” ketamine required only 15 minutes.Details
Pax Neuroscience was awarded an STTR grant, entitled “Using a novel model of antidepressant efficacy to discover new compounds and personalized treatments.“ The funds, from the National Institute of Mental Health (NIMH) are being used to perfect and miniaturize the assay of Gsalpha in lipid raft and non-raft fractions from blood cells and to develop a predictive medicine platform for depression, using blood cells extracted from individual patients, screened for response to a panel of antidepressants using Pax’s depression biomarker Technology (MoodMarkPREDICT).Details
Each year, the Office of Technology Management celebrates UIC faculty inventors. The Innovator of the Year Award recognizes researchers who have advanced their inventions toward commercialization. The Inventor of the Year Award honors researchers whose discoveries have the potential for significant impact. Mark Rasenick, UIC Innovator of the Year, developed a blood test that can identify…Details
Millions of Americans are prescribed antidepressants each year, yet it typically takes weeks for patients to feel any effects. Researchers could never explain the peculiarity, but new work published in July offers a clue. The study, from researchers at University of Illinois at Chicago, examined rat brain cells and focused on lipid rafts — an area of the cell membrane that specializes in organizing important molecules.Details
Mark M. Rasenick, Distinguished University Professor in physiology and biophysics and psychiatry and founding director of the Neuroscience Program at the University of Illinois at Chicago College of Medicine, has been named a Fellow by the American Association for the Advancement of Science. Election as a Fellow is an honor bestowed upon AAAS members by their peers.Details